diff --git a/Makefile b/Makefile
index dcae5bb3..8c89f3b2 100644
--- a/Makefile
+++ b/Makefile
@@ -27,6 +27,16 @@ CFLAGS += -Dstatic_assert=_Static_assert
 LDFLAGS += \
 	-lbsd \
 	-lnetwork
+else ifeq ($(UNAME_S),OpenBSD)
+BUILD_TYPES := debug release
+CFLAGS += \
+	-Wno-unknown-warning-option
+LDFLAGS += \
+	-lexecinfo \
+	-lc++abi
+HAVE_ANDROID := 0
+HAVE_LINUX_IOS := 0
+HAVE_WIN := 0
 else
 $(error Unexpected host platform $(UNAME_S).)
 endif
@@ -292,6 +302,14 @@ else ifeq ($(UNAME_S),Haiku)
 		deps/libuv/src/unix/no-proctitle.c \
 		deps/libuv/src/unix/posix-hrtime.c \
 		deps/libuv/src/unix/posix-poll.c
+else ifeq ($(UNAME_S),OpenBSD)
+	UV_SOURCES_unix += \
+		deps/libuv/src/unix/bsd-ifaddrs.c \
+		deps/libuv/src/unix/kqueue.c \
+		deps/libuv/src/unix/no-proctitle.c \
+		deps/libuv/src/unix/openbsd.c \
+		deps/libuv/src/unix/posix-hrtime.c \
+		deps/libuv/src/unix/random-getentropy.c
 endif
 UV_SOURCES_android := \
 	deps/libuv/src/unix/random-getentropy.c
@@ -558,9 +576,11 @@ debug release $(MACOS_TARGETS) $(IOS_TARGETS) $(IOSSIM_TARGETS): LDFLAGS += \
 	-lssl \
 	-lcrypto
 ifneq ($(UNAME_S),Haiku)
+ifneq ($(UNAME_S),OpenBSD)
 debug release $(MACOS_TARGETS) $(IOS_TARGETS) $(IOSSIM_TARGETS): LDFLAGS += \
 	-ldl
 endif
+endif
 $(WINDOWS_TARGETS): LDFLAGS += \
 	-lssl \
 	-lcrypto \
diff --git a/deps/quickjs/quickjs.c b/deps/quickjs/quickjs.c
index a0d5863d..88b331c4 100644
--- a/deps/quickjs/quickjs.c
+++ b/deps/quickjs/quickjs.c
@@ -1680,7 +1680,7 @@ static inline size_t js_def_malloc_usable_size(void *ptr)
     return malloc_size(ptr);
 #elif defined(_WIN32)
     return _msize(ptr);
-#elif defined(EMSCRIPTEN) || defined(__HAIKU__)
+#elif defined(EMSCRIPTEN) || defined(__HAIKU__) || defined(__OpenBSD__)
     return 0;
 #elif defined(__linux__)
     return malloc_usable_size(ptr);
@@ -1754,7 +1754,7 @@ static const JSMallocFunctions def_malloc_funcs = {
     malloc_size,
 #elif defined(_WIN32)
     (size_t (*)(const void *))_msize,
-#elif defined(EMSCRIPTEN) || defined(__HAIKU__)
+#elif defined(EMSCRIPTEN) || defined(__HAIKU__) || defined(__OpenBSD__)
     NULL,
 #elif defined(__linux__)
     (size_t (*)(const void *))malloc_usable_size,
diff --git a/src/main.c b/src/main.c
index a6348655..4e5f438f 100644
--- a/src/main.c
+++ b/src/main.c
@@ -18,10 +18,13 @@
 
 #if !defined(_WIN32) && !defined(__APPLE__) && !defined(__HAIKU__)
 #include <signal.h>
-#include <sys/prctl.h>
 #include <sys/resource.h>
 #endif
 
+#if defined(__linux__)
+#include <sys/prctl.h>
+#endif
+
 #if defined(__APPLE__)
 #include <TargetConditionals.h>
 #endif
@@ -362,7 +365,7 @@ static void _shed_privileges()
 		perror("setrlimit(RLIMIT_NPROC, {0, 0})");
 		exit(-1);
 	}
-#if !defined(__MACH__)
+#if !defined(__MACH__) && !defined(__OpenBSD__)
 	if (setrlimit(RLIMIT_LOCKS, &zeroLimit) != 0)
 	{
 		perror("setrlimit(RLIMIT_LOCKS, {0, 0})");
@@ -484,7 +487,7 @@ static int _tf_command_sandbox(const char* file, int argc, char* argv[])
 		return 2;
 	}
 
-#if !defined(_WIN32) && !defined(__APPLE__) && !defined(__HAIKU__)
+#if defined(__linux__)
 	prctl(PR_SET_PDEATHSIG, SIGHUP);
 #endif
 	tf_task_t* task = tf_task_create();
@@ -607,7 +610,7 @@ static void _startup(int argc, char* argv[])
 		_backtrace_error,
 		NULL);
 
-#if !defined(_WIN32) && !defined(__APPLE__) && !defined(__HAIKU__)
+#if defined(__linux__)
 	prctl(PR_SET_PDEATHSIG, SIGKILL);
 #endif
 	tf_mem_replace_uv_allocator();
diff --git a/src/mem.c b/src/mem.c
index 0f9eed09..10439826 100644
--- a/src/mem.c
+++ b/src/mem.c
@@ -394,17 +394,29 @@ size_t tf_mem_get_uv_malloc_size()
 	return s_uv_malloc_size;
 }
 
+#if defined(__OpenBSD__)
+void* _tf_tls_alloc(size_t size)
+#else
 void* _tf_tls_alloc(size_t size, const char* file, int line)
+#endif
 {
 	return _tf_alloc(&s_tls_malloc_size, size);
 }
 
+#if defined(__OpenBSD__)
+void* _tf_tls_realloc(void* ptr, size_t size)
+#else
 void* _tf_tls_realloc(void* ptr, size_t size, const char* file, int line)
+#endif
 {
 	return _tf_realloc(&s_tls_malloc_size, ptr, size);
 }
 
+#if defined(__OpenBSD__)
+void _tf_tls_free(void* ptr)
+#else
 void _tf_tls_free(void* ptr, const char* file, int line)
+#endif
 {
 	_tf_free(&s_tls_malloc_size, ptr);
 }
diff --git a/src/task.c b/src/task.c
index 6e1b771a..e45bec40 100644
--- a/src/task.c
+++ b/src/task.c
@@ -33,7 +33,7 @@
 #include <unistd.h>
 #endif
 
-#if !defined(__APPLE__)
+#if !defined(__APPLE__) && !defined(__OpenBSD__)
 #include <malloc.h>
 #endif
 
diff --git a/src/tests.c b/src/tests.c
index 9afaf817..9c9ead8b 100644
--- a/src/tests.c
+++ b/src/tests.c
@@ -16,6 +16,10 @@
 #define WEXITSTATUS(x) (x)
 #endif
 
+#if defined(__OpenBSD__)
+#include <sys/wait.h>
+#endif
+
 #if defined(__APPLE__)
 #include <TargetConditionals.h>
 #endif